Lab Reagents
Human IgG antibody Laboratories manufactures the invivogen thp1 nlrc4 reagents distributed by Genprice. The Invivogen Thp1 Nlrc4 reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact InVivoGen. Other Invivogen products are available in stock. Specificity: Invivogen Category: Thp1 Group: Nlrc4
Nlrc4 information
Anti-CARD12/NLRC4 Antibody |
PB9673 |
BosterBio |
100ug/vial |
EUR 294 |
Mouse NLRC4 shRNA Plasmid |
20-abx983002 |
Abbexa |
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Rat NLRC4 shRNA Plasmid |
20-abx988957 |
Abbexa |
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Human NLRC4 shRNA Plasmid |
20-abx961713 |
Abbexa |
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NLRC4 Polyclonal Conjugated Antibody |
C27907 |
SAB |
100ul |
EUR 397 |
NLRC4 Polyclonal Conjugated Antibody |
C30909 |
SAB |
100ul |
EUR 397 |
NLRC4(Phospho-Ser-533) Antibody |
13336-100ul |
SAB |
100ul |
EUR 333 |
NLRC4(Phospho-Ser-533) Antibody |
13336-50ul |
SAB |
50ul |
EUR 239 |
NLRC4 ELISA Kit (Mouse) (OKEH04227) |
OKEH04227 |
Aviva Systems Biology |
96 Wells |
EUR 662 |
Description: Description of target: Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. It senses pathogenic proteins of the type III secretion system (T3SS) and type IV secretion system (T4SS) such as flagellin and PrgJ-like rod proteins via the Naip proteins (Naip1, Naip2 or Naip5): specific Naip proteins recognize and bind pathogenic proteins, driving assembly and activation of the NLRC4 inflammasome. The NLRC4 inflammasome senses Gram-negative bacteria such as L.pneumophila and P.aeruginosa, enteric pathogens S.typhimurium (Salmonella) and S.flexneri and fungal pathogen C.albicans. In intestine, the NLRC4 inflammasome is able to discriminate between commensal and pathogenic bacteria and specifically drives production of interleukin-1 beta (IL1B) in response to infection by Salmonella or P.aeruginosa. In case of L.pneumophila infection the inflammasome acts by activating caspase-7.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.083 ng/mL |
NLRC4 ELISA Kit (Bovine) (OKEH08312) |
OKEH08312 |
Aviva Systems Biology |
96 Wells |
EUR 1092 |
Description: Description of target: ;Species reactivity: Bovine;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.053ng/ml |
Nlrc4 ORF Vector (Mouse) (pORF) |
ORF051436 |
ABM |
1.0 ug DNA |
EUR 506 |
NLRC4 ORF Vector (Human) (pORF) |
ORF007107 |
ABM |
1.0 ug DNA |
EUR 95 |
Flagellin NLRC4 Mutant Recombinant Protein |
90-306 |
ProSci |
10 ug |
EUR 390.5 |
Description: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (NLRC4 Mutant)(rec. ) is only detected by TLR5 not by NLRC4. |