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A method combining blue native polyacrylamide gel electrophoresis with liquid chromatography tandem-mass spectrometry to detect circulating immune complexes between therapeutic monoclonal antibodies and anti-drug antibodies in animals.
A method combining blue native polyacrylamide gel electrophoresis with liquid chromatography tandem-mass spectrometry to detect circulating immune complexes between therapeutic monoclonal antibodies and anti-drug antibodies in animals.
Posted by Troy
Therapeutic monoclonal antibodies have the potential to cause an unwanted immune response, resulting in anti-drug antibody production (fennel). Fennel binding to drugs and subsequent formation of the
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